Circulating Interleukins and Risk of Multiple Sclerosis: A Mendelian Randomization Study
نویسندگان
چکیده
منابع مشابه
Obesity and Multiple Sclerosis: A Mendelian Randomization Study
BACKGROUND Observational studies have reported an association between obesity, as measured by elevated body mass index (BMI), in early adulthood and risk of multiple sclerosis (MS). However, bias potentially introduced by confounding and reverse causation may have influenced these findings. Therefore, we elected to perform Mendelian randomization (MR) analyses to evaluate whether genetically in...
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Dr. David Goltzman is not included in the author byline. He should be listed as the sixth author and affiliated with Department of Medicine, McGill University, Montreal, Quebec, Canada. The contributions of this author are as follows: Contributed to the application of the methods and the interpretation of the findings. The correct citation is: Mokry LE, Ross S, Ahmad OS, Forgetta V, Smith GD, G...
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BACKGROUND Observational studies have demonstrated an association between decreased vitamin D level and risk of multiple sclerosis (MS); however, it remains unclear whether this relationship is causal. We undertook a Mendelian randomization (MR) study to evaluate whether genetically lowered vitamin D level influences the risk of MS. METHODS AND FINDINGS We identified single nucleotide polymor...
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ژورنال
عنوان ژورنال: Frontiers in Immunology
سال: 2021
ISSN: 1664-3224
DOI: 10.3389/fimmu.2021.647588